唐和斌

发布时间:2020-10-14 浏览次数:


 

唐和斌:教授、博士生导师

出生年月:1970.11        民族:汉族

学历学位:药学博士      学科专业:药理学

电话: 027-67842332     

电子邮箱:hbtang2006@mail.scuec.edu.cn

研究方向包括:肝损伤机制及民族药物干预;皮肤创伤修复的民族药物药理学机制研究。

 

唐和斌教授,博士生导师,拥有医学学士学位和药学博士学位。20054月至20093月,担任日本国立广岛大学药学院助理教授。20094月回国后,担任环球360管理网药学院教授。

主要从事针对肝损伤(涵盖脂肪肝、肝纤维化、肝癌等慢性肝病)及皮肤创伤(包括烧烫伤、糖尿病足溃疡、银屑病、特应性皮炎、痤疮、妊娠纹等皮肤屏障损伤性疾病)的发病机制研究,同时致力于这些疾病的民族药物干预及其药理效应机制的深入剖析。尤其在糖尿病足溃疡、烧伤、妊娠纹等临床创伤修复领域的科学难题上取得了突破性进展,成功构建了“快速无痕修复”这一独特的科技壁垒。

作为项目负责人,先后主持日本和中国的国家自然科学基金项目6项,以及省部级科研项目和企业委托项目近30项。在Journal of EthnopharmacologyNeuropharmacology等期刊上发表80余篇论文;获得授权的国家发明专利28项,其中15项已经完成了科技成果转化。

近五年的代表性研究论文(*为通讯作者

1.      Ma SY, Yin X, Zhang Z, Li YS, Tang HB*. Topical frankincense treatment on relieving high-risk diabetic foot in rats by reducing inflammation and improving microcirculation. Frontiers in Pharmacology. 2025, 16: 1564236. doi: 10.3389/fphar.2025.1564236. eCollection 2025.

2.      Li TT, Wen LY, Meng SS, Li YS, Tang HB*. Oral administration of ethanol extract from Gynura procumbens stems corrects kidney injury and renal anemia in chronic kidney disease. Frontiers in Pharmacology. 2025, 15:1476735. doi: 10.3389/fphar.2024.1476735. eCollection 2024.

3.      Zhang Z, Ma SY, Yin X, Li YS, Tang HB*. Topical frankincense treatment for frostbite based on microcirculation improvements. Journal of Ethnopharmacology. 2025, 336:118728. doi: 10.1016/j.jep.2024.118728.

4.      Yin X, Gu HW, Ning D, Li YS, Tang HB*. Testosterone Exacerbates the Formation of Liver Cancer Induced by Environmental N-Nitrosamines Exposure: Potential Mechanisms and Implications for Human Health. OncoTargets and Therapy. 2024, 17: 395-409. doi: 10.2147/OTT.S456746.

5.      Zhai SY, Gu HW, Wang C, Li YS, Tang HB*. Gynura procumbens and selected metabolites: Amelioration of depressive-like behaviors in mice and risperidone-induced hyperprolactinemia in rats. Biomed Pharmacother. 2024, 173: 116361. doi: 10.1016/j.biopha.2024.116361.

6.      Yin X, Li YS, Ye SZ, Zhang T, Zhang YW, Xi Y, Tang HB. Promotion Effect of Coexposure to a High-Fat Diet and Nano-Diethylnitrosamine on the Progression of Fatty Liver Malignant Transformation into Liver Cancer. International Journal of Molecular Sciences. 2023, 24(18): 14162. doi: 10.3390/ijms241814162.

7.      Meng SS, Gu HW, Zhang T, Li YS, Tang HB*. Gradual deterioration of fatty liver disease to liver cancer via inhibition of AMPK signaling pathways involved in energy-dependent disorders, cellular aging, and chronic inflammation. Frontiers in Oncology. 2023, 13: 1099624. doi: 10.3389/fonc.2023.1099624.

8.      Yin X, Hong J, Tang HB*, Liu M, Li YS. Enhanced healing of oral chemical burn by inhibiting inflammatory factors with an oral administration of shengFu oil. Frontiers in Pharmacology. 2022, 13: 913098. doi: 10.3389/fphar.2022.913098.

9.      Wang C, Huang XL, Mu YM, Li YS, He YM, Tang HB*. Synergistic effects of trans-p-coumaric acid isolated from the ethanol extract of Gynura procumbens in promoting intestinal absorption of chlorogenic acid and reversing alcoholic fatty liver disease. Journal of Ethnopharmacology. 2022, 295: 115407. doi: 10.1016/j.jep.2022.115407.

10.  Zhang T, Gu HW, Gao JX, Li YS, Tang HB*. Ethanol supernatant extracts of Gynura procumbens could treat nanodiethylnitrosamine-induced mouse liver cancer by interfering with inflammatory factors for the tumor microenvironment. Journal of Ethnopharmacology. 2022, 285: 114917. doi: 10.1016/j.jep.2021.114917.

11.  Li YS, Zhang J, Tian GH, Shang HC, Tang HB*. Kirenol, darutoside and hesperidin contribute to the anti-inflammatory and analgesic activities of Siegesbeckia pubescens makino by inhibiting COX-2 expression and inflammatory cell infiltration. Journal of Ethnopharmacology. 2021, 268: 113547. doi: 10.1016/j.jep.2020.113547.

12.  Hong J, Chen XZ, Peng YG, Zhang WK, Tang HB*, Li YS. Nanoparticle-Encapsulated Liushenwan Could Treat Nanodiethylnitrosamine-Induced Liver Cancer in Mice by Interfering With Multiple Critical Factors for the Tumor Microenvironment. Frontiers in Pharmacology. 2020, 11: 1052. doi: 10.3389/fphar.2020.01052.

13.  Zheng L, Li XY, Huang FZ, Zhang XT, Tang HB*, Li YS, Zhang WK, Li XJ, Tian GH. Effect of electroacupuncture on relieving central post-stroke pain by inhibiting autophagy in the hippocampus. Brain Research. 2020, 1733: 146680. DOI: 10.1016/j.brainres.2020.146680.

 

近年主持的国家自然科学基金项目

1. 基于β-catenin/COX-2炎性环路探究外用生肤油促进糖尿病足病快速修复的效应机制,2021年国家自然科学基金面上项目;

2. 平卧菊三七干预“β-catenin/COX-2”炎性环路的防治肝癌机制研究. 2016年国家自然科学基金面上项目;

3. 生肤油促进度烫伤皮肤无瘢痕修复的机制研究。2013年国家自然科学基金面上项目;

4. Wnt/β-catenin信号通路调控原发性肝癌发生的机制研究. 2011年国家自然科学基金青年项目;

5. 非神经细胞对背根神经节神经细胞内P物质释放的调控机制。2010年国家自然科学基金面上项目;

作者:   责编:   审核:   上传:

地址:中国-湖北-武汉 民族大道182号环球360管理网药学院 邮编:430074
电话:027-67841196  Fax: 027-67841196
© 2016 环球360管理网药学院